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Senin, 21 Mei 2012

Report: Schools key to fighting America's obesity

WASHINGTON — Fighting obesity will require changes everywhere Americans live, work, play and learn, says a major new report that outlines dozens of options — from building more walkable neighborhoods to zoning limits on fast-food restaurants to selling healthier snacks in sports arenas.

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But schools should be a national focus because that's where children spend most of their day, eat a lot of their daily calories — and should be better taught how to eat healthy and stay fit, the influential Institute of Medicine said Tuesday.

Among the most controversial of the recommendations: Communities could consider a tax on sugary sodas and offering price breaks for healthier beverage choices.

That prompted outrage from the American Beverage Association.

"Advocating discriminatory policies that uniquely focus on sugar-sweetened beverages is the wrong approach," said an association statement that added those drinks account for just 7 percent of calories in the average person's diet.

Most of us know we should eat less and move more. But the institute makes clear this isn't just an individual but a societal problem: For a host of reasons, sedentary lives have become the norm and we're surrounded by cheap, high-calorie foods.

The new report offers a roadmap of the most promising strategies to change that — and argues that the solutions can't be implemented piecemeal.

"Each of us has this role. We can't sit back and let the schools do it, or let a mayor do it or think somehow the federal government's going to solve it," said report co-author William Purcell III, former mayor of Nashville, Tenn. "These recommendations require concerted effort among all."

A health advocacy group urged governments, industry and schools to adopt the recommendations.

"The country has begun to address obesity but we are still doing far too little given the tremendous burden it places on our health and health care costs," said Margo Wootan of the Center for Science in the Public Interest.

Two-thirds of U.S. adults and almost a third of children are either overweight or obese, and progress to stop this epidemic has been too slow, the Institute of Medicine concluded.

For schools, it recommended that students get at least 60 minutes of physical activity every day — a combination of physical education, recess and other activities. Many schools have slashed P.E. and cut into recess in recent years in an effort to increase learning time amid tighter budgets. The report also says schools should serve healthier foods, backing national school nutrition standards, and teach nutrition.

Other recommendations include:

—Restaurants should ensure that at least half of kids' meals comply with federal dietary guidelines, without charging more for the healthier options.

—Healthier foods should be routinely available everywhere, from shopping malls to sports arenas.

—More food companies should improve how they market to children — and if they don't, the government should step in and mandate changes.

—To make physical activity routine, communities should be designed with safe places to walk and exercise.

—Public and private insurers should ensure better access to obesity screening, preventive services and treatments.

—Employers should expand workplace wellness programs.

—The president should appoint a task force to evaluate the impact of U.S. agriculture policies on obesity.

The Institute of Medicine, an arm of the National Academy of Sciences, is an independent organization that advises the government.

Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Sabtu, 17 Maret 2012

How Salmonella Avoids The Body's Immune Response Offers Approaches To Fighting Powerful Gut Infections

UC Irvine researchers have discovered how salmonella, a bacterium found in contaminated raw foods that causes major gastrointestinal distress in humans, thrives in the digestive tract despite the immune system's best efforts to destroy it.

Their findings help explain why salmonella is difficult to eradicate and point to new approaches for possible treatments. Most people infected with salmonella suffer from diarrhea, fever and abdominal cramps for up to seven days before the infection resolves.

Lead researcher Manuela Raffatellu, a UCI assistant professor of microbiology & molecular genetics, and colleagues identified a novel molecular mechanism that allows salmonella to survive. Results of their study appear in the March issue of Cell Host & Microbe.

Pathogens like salmonella flourish and cause disease in humans through a process by which they acquire metal ions, such as zinc, from the body. One of the body's key immune responses is to flood the infected area with antimicrobial proteins that include calprotectin, which removes zinc. Without enough of this vital element, most pathogens eventually die.

Raffatellu's team found, however, that salmonellae overcome this immune response by expressing specialized transporter proteins that enable the bacteria to acquire zinc in spite of calprotectin reducing the amount available in the digestive tract. This distinctive mechanism lets salmonella continue proliferating.

At the same time, calprotectin inadvertently promotes salmonella growth by killing the microbes that normally reside within the intestines and help the immune system battle pathogenic bacteria.

"We're beginning to learn more about the mechanisms that allow pathogens like salmonella to evade our natural defenses and make us sick," Raffatellu said. "In light of this, if we can devise therapies that block the acquisition of zinc and other metals by salmonella specifically, we can fight this infection."

Additionally, she said, the new findings may have relevance for other illnesses, such as inflammatory bowel disease and colon cancer, in which high levels of calprotectin are detected.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our infectious diseases / bacteria / viruses section for the latest news on this subject. Also contributing to the study, which was supported by grants from the National Institutes of Health, were Janet Z. Liu, Stefan Jellbauer, Adam Poe, Vivian Ton, Michele Pesciaroli, Martin Hosking, Robert A. Edwards and Thomas E. Lane of UCI; Thomas Kehl-Fie, Nicole A. Restrepo, Walter J. Chazin and Eric P. Skaar of Vanderbilt University; Andrea Battistoni of the University of Rome; Thomas Vogl and Johannes Roth of the University of Munster, Germany; and Paolo Pasquali of the Superior Health Institute in Rome.
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